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Pure Appl. Chem., 1988, Vol. 60, No. 8, pp. 1357-1362

Synthesis and reactivity of platinum and palladium complexes with α-amino acids, peptides and derivatives thereof: platinum (II) as amino protecting group

Wolfgang Beck

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  • Preciado Sara, Mendive-Tapia Lorena, Albericio Fernando, Lavilla Rodolfo: Synthesis of C-2 Arylated Tryptophan Amino Acids and Related Compounds through Palladium-Catalyzed C–H Activation. J. Org. Chem. 2013, 78, 8129. <>
  • Beck Wolfgang: Metal Complexes of Biologically Important Ligands, CLXXVI.[1] Formation of Peptides within the Coordination Sphere of Metal Ions and of Classical and Organometallic Complexes and Some Aspects of Prebiotic Chemistry. Z anorg allg Chem 2011, 637, 1647. <>
  • Kim Eunsuk, Rye Peter T., Essigmann John M., Croy Robert G.: A bifunctional platinum(II) antitumor agent that forms DNA adducts with affinity for the estrogen receptor. J  Inorg Biochem 2009, 103, 256. <>
  • Ponikwar Walter, Hauck Thomas, Beck Wolfgang: Metallkomplexe mit biologisch wichtigen Liganden. CLXIII N,O-Chelatkomplexe mit Propargylglycinat. Z anorg allg Chem 2006, 632, 1983. <>
  • Bera Sujit K., Chandra Swapan K., De Gauri S.: Substitution of aqua ligands fromcis-[Pt(en)(H2O)2](ClO4)2 andcis-[Pt(dmen)(H2O)2](ClO4)2 (en = ethylenediamine, dmen =N N′-dimethyl ethylenediamine) by glycine in aqueous medium—a kinetic and mechanistic approach. Int J Chem Kinet 2005, 37, 489. <>
  • Gyurcsik Béla, Nagy László: Carbohydrates as ligands: coordination equilibria and structure of the metal complexes. Coord Chem Rev - 2000, 203, 81. <>
  • McCurdie Mary Pat, Belfiore Laurence A.: Solid-state complexes of poly(L-histidine) with metal chlorides from the first row of thed-block. J Polym Sci B Polym Phys 1999, 37, 301. <<301::AID-POLB4>3.0.CO;2-H>
  • Haas Katharina, Ehrenstorfer-Schäfers Eva-Maria, Polborn Kurt, Beck Wolfgang: Bis(dipeptide ester–H+) Complexes of Palladium(II) – Precursors for the Formation of Cyclotetrapeptides. Eur J Inorg Chem 1999, 1999, 465. <<465::AID-EJIC465>3.0.CO;2-5>
  • Severin Kay, Bergs Ralph, Beck Wolfgang: Biometallorganische Chemie – Übergangsmetallkomplexe mit α-Aminosäuren und Peptiden. Angew Chem 1998, 110, 1722. <<1722::AID-ANGE1722>3.0.CO;2-N>
  • Navarro R., García J., Urriolabeitia E.P., Cativiela C., Diaz-de-Villegas M.D.: Metal complexes of biologically important ligands: Synthesis of amino acidato complexes of PdII containing a C,N-cyclometallated group as an ancillary ligand. J Organomet Chem 1995, 490, 35. <>
  • Iakovidis A., Hadjiliadis N.: Complex compounds of platinum (II) and (IV) with amino acids, peptides and their derivatives. Coord Chem Rev - 1994, 135-136, 17. <>
  • Zhu Longgen, M. Kostić Nenad: Hydrolytic cleavage of peptides by palladium(II) complexes is enhanced as coordination of peptide nitrogen to palladium(II) is suppressed. Inorg Chim Ada 1994, 217, 21. <>
  • Lombardi Angela, Maglio Ornella, Pavone Vincenzo, Di Blasio Benedetto, Saviano Michele, Nastri Flavia, Pedone Carlo, Benedetti Ettore: Pt(II) complexes of amino acids and peptides III. X-ray diffraction study of [Cl(Ph3P)Pt(H-Aib-O)]. Inorg Chim Ada 1993, 204, 87. <>
  • Lombardi Angela, Maglio Ornella, Benedetti Ettore, Di Blasio Benedetto, Saviano Michele, Nastri Flavia, Pedone Carlo, Pavone Vincenzo: Pt(II) complexes of amino acids and peptides II. Structural analysis of trans-[Cl2-Pt-(H-Aib-OH)2n] and trans-[Pt-(H-Aib-O−)2]. Inorg Chim Ada 1992, 196, 241. <>
  • Apfelbaum Haim C., Blum Jochanan, Mandelbaum-Shavit Frederika: Preparation and anticancer activity of two tryptamine derived platinum complexes. Inorg Chim Ada 1991, 186, 243. <>
  • Schwarz Frank, Lippert Bernhard, Iakovidis Akis, Hadjiliadis Nick: Ternary complexes of cis-(NH3)2Pt(II) with model nucleobases (1-methylcytosine, 9-methylguanine) and N- and O-bound amino acids (gly, ala). Inorg Chim Ada 1990, 168, 275. <>
  • Wagner Barbara, Taubald Ute, Beck Wolfgang: Metallkomplexe mit biologisch wichtigen Liganden, LI. Reaktionen von α-Aminosäuren mit Hexachloropalladat(IV). Stabilisierung von 1-Pyrrolin an Palladium(II). Chem Ber 1989, 122, 1031. <>